Kyowa Kirin International is headquartered in the Scottish Borders with full commercial operations in the UK and Ireland.
We have a range of products in the UK and Ireland, covering the following therapeutic areas:
XLH, or X-linked hypophosphataemia, is a rare, hereditary, chronic and progressive musculoskeletal disorder resulting from excess FGF23 production. In XLH, excessive levels of FGF23 result in renal phosphate wasting and decreased active vitamin D levels, causing chronic hypophosphataemia. In the majority of cases XLH is inherited in an X-linked pattern and it is estimated to affect approximately 1 in 20,000 to 1 in 60,000 people. XLH is associated with functional limitations and a reduced quality of life.
Cutaneous T-cell lymphomas (CTCL) are primary cutaneous lymphomas (PCLs) of T-cell origin, and are rare, serious and potentially life-threatening, forms of non-Hodgkin lymphoma that primarily affect the skin with pink or erythematous scaly patches and plaques. Mycosis fungoides (MF) is the most common type of cutaneous T-Cell lymphoma. Sézary syndrome (SS) is the leukemic form of the disease in which erythroderma is accompanied by measurable blood involvement with Sézary cells.